https://www.winter-lab.com/home daily 1.0 2026-04-01 https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/1551953952810-AT0UOHP9COHKAIBPLMFV/Targeting+MYC-HighRes.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/5b09f723-2887-4215-8ba0-a4115777f2c1/Screenshot+2026-01-21+at+13.37.35.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/ca496276-a365-4615-8144-2c0be4e98f13/JuliaBeaucamp-031.jpg home - Julie Beaucamp Julie obtained her Bachelors and Masters in Biochemistry from the University of Heidelberg. For her Bachelor thesis, she joined the Lyko group at the DKFZ, investigating epigenetics and chitin biosynthesis in marbled crayfish. During her Master thesis in the Böttcher Lab at the University of Vienna, she synthesized lipoteichoic acids and studied their interactions with bacteriophages. As a PhD student in the Winter lab, Julie will focus on rewiring cell death in cancer cells via induced protein proximity. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/810a8569-7f3e-4d5f-9b15-cf6d485dd1a2/CarolinaCaso-009.jpg home - Carolina Caso Carolina obtained her MSc in Pharmaceutical Sciences from La Sapienza, University of Rome. She pursued her doctoral studies at ETH Zürich in the group of Prof. Karl-Heinz Altmann, working on the total synthesis of natural products. As a postdoctoral fellow in the Winter lab, she is focusing on the synthesis of libraries by means of a direct-to-biology approach to identify new molecular glue degraders. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/62658177-e878-4e85-b40e-4594941611b8/MarkoCigler-007.jpg home - Marko Cigler Initially trained as a chemist in Zagreb, Marko completed his PhD in the lab of Kathrin Lang at the Technical University Munich where he worked on genetic code expansion. He joined the lab as a postdoctoral fellow in March 2020 to work on molecular glue degraders. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/9d0503df-f14f-4242-aed9-8fbb9e2affd3/JoseCisneros-004.jpg home - Jose Cisneros Jose earned his PhD in medicinal chemistry in the group of Maria Luz Lopez-Rodriguez at Universidad Complutense in Madrid working in the synthesis of molecules involved in the regulation of the endocannabinoid system (ECS). He continued his work in the field of medicinal chemistry in the group of William Jorgensen at Yale University as a postdoctoral fellow and associate research scientist. He joined the lab in 2020 as a research chemist to work in the synthesis of molecular glues and PROTACs. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/e94b9d7b-2a0c-4331-b0bf-490884f0c5d0/KevinDong-018.jpg home - Kevin Dong Before his doctoral studies, Kevin served as a Moonshot Venture Fellow at Apollo Health Ventures, where he co-founded Thymofox, a biotechnology company focused on small-molecule approaches to thymic rejuvenation. He then earned his PhD in Biological and Biomedical Sciences at Harvard Medical School in the laboratory of Steven Gygi. During this time, he developed a chemoproteomic platform to decode the endogenous degradation pathways of the short-lived proteome and established CysDig, a novel proteomic workflow for targeted covalent drug discovery. Now, in the Winter Lab, Kevin leverages functional genomics to perturb the proteome at scale in a programmable manner. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/cc7f22f2-a6ec-4371-9f70-4ff6c2d069b3/HannahHaller-017.jpg home - Hannah Haller Hannah joined the lab as Laboratory Technician in April 2024. She finished the Master program Molecular Biotechnology at FH Campus Wien and stayed at Karolinska Institutet, Stockholm for her Master research. Hannah has a great interest in cancer research and targeted protein degradation. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/4e84e9f1-f8c6-4831-88f9-08e4c8235748/MatthiasHinterndorfer-032.jpg home - Matthias Hinterndorfer Matthias obtained his PhD from the Zuber lab at the Institute of Molecular Pathology Vienna, where he established temporally resolved CRISPR screens that led to the discovery of the vertebrate nuclear proteasome import pathway. In his work as a Senior Research Scientist in the Winter lab, he is looking to combine his interests in genetic screening and proteasome biology to elucidate the genetic determinants underlying chemically induced targeted protein degradation. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/e156612a-9d32-434b-ad55-72cc90513e14/LisaHoffmann-Haas-030+Scientific+Coordinator+Winter+Lab.jpg home - Lisa Hoffmann-Haas Lisa earned her MSc in Molecular Medicine from the University of Vienna, which included a one-year research internship at the MRC Cancer Unit in Cambridge, UK. She completed her doctoral studies in the Obenauf lab at the Research Institute of Molecular Pathology (IMP) in Vienna, where her research focused on the mechanistic intersection of targeted therapy and immunotherapy in melanoma. Following her PhD, Lisa spent four years as an editor at Nature Cancer in Berlin, managing a diverse portfolio ranging from fundamental drug discovery to clinical trials. In 2026, she joined the Winter lab as a Scientific Project Coordinator. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/c71878e9-2dab-48cc-9619-95035ffd672d/DavidHoi-016.jpg home - David Hoi Initially trained as chemist, David completed his PhD in Molecular Biology at the Institute of Molecular Pathology in Vienna, where he studied novel targeted protein degradation strategies in pathogenic bacteria. He joined the Winter Lab as a postdoctoral fellow in November 2023 aiming to develop chemical solutions to rewire transcriptional regulation in cancer. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/625a19e8-61e0-4f72-a5b2-77c3466f3d29/ChrysanthinKagiou-015.jpg home - Chrysanthi Kagiou Chrysanthi received her master's degree in Molecular Mechanisms of Disease in the Hobo lab at Radboud University in The Netherlands focusing on hematological malignancies. She completed her master thesis in the Weigelin group at Werner Siemens Imaging Center. In 2020, Chrysanthi joined the Loizou Lab at the Institute of Cancer Research in Vienna, using advanced genome editing technologies to study cancer-associated mutations on DNA damage response genes. Chrysanthi joined Winter lab as a PhD student in June 2022, focusing on identifying novel molecular glue degraders in different cell states. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/d0a75438-a6b0-460b-9df0-28edc511d914/LisaKainacher-018.jpg home - Lisa Kainacher Lisa studied Molecular Biotechnology in her BSc at the FH Campus Wien. She joined the Christodoulou lab at University College London to investigate the structural underpinnings of protein misfolding. She then studied Molecular Medicine in her MSc at the University of Vienna. For her master research, she joined the Murray lab at the Max Planck Institute of Biochemistry in Munich where she worked on the complex role of tryptophan metabolism in human cancers and its association with ferroptotic cell death. Lisa joined the Winter lab in autumn 2023 and in her PhD she will focus on the rewiring of transcriptional networks using small molecule libraries and chemical screens to exploit cancer vulnerabilities. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/2edbdc51-9671-4840-8d66-9b5f3f34d9c7/KatharinaKladnik-038.jpg home - Katharina Kladnik Katharina joined the Winter lab in 2022 as Technical Assistant. She completed her Masters studies in molecular biotechnology at the FH Campus Wien, where her interests focused around cancer and biopharmaceutical research. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/d5c7a102-b396-4523-96c9-7d4933a2a552/JurajKonc-005.jpg home - Juraj Konc Juraj obtained an MSc in Organic Chemistry from Charles University in Prague, where he worked on medicinal chemistry of nucleoside analogs in Prof. Michal Hocek’s group at IOCB Prague. He completed his PhD at the Yusuf Hamied Department of Chemistry at the University of Cambridge with Prof. Gonçalo Bernardes, focusing on the chemical modification of biomolecules and bioorthogonal chemistry. Juraj subsequently joined Prof. Kaan Boztug’s group at St. Anna Children’s Cancer Research Institute as a postdoctoral fellow, developing novel therapeutic approaches for high-risk neuroblastoma. In June 2025, he moved to the Winter lab, where he continues these efforts with a particular interest in degrader–antibody conjugates. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/f64388c9-1626-4567-8707-26fe40112751/SeverinLechner-015.jpg home - Severin Lechner Initially trained as biochemist, Severin completed his PhD in the lab of Bernhard Kuster at the Technical University of Munich, where he focused on (chemo-)proteomic drug target deconvolution methods. As a postdoctoral fellow in the Winter lab, Severin is hunting for small molecules that allow to redirect transcription-regulating protein complexes. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/a4a8e6c5-bb2f-48b8-aacd-90810c994b1a/MaurizLichtenstein-006.jpg home - Mauriz Lichtenstein Mauriz obtained his BSc and MSc in Biochemistry from the Freie Universität Berlin. In his undergraduate research at the Taylor lab at the Max-Planck-Institute for Infection Biology in Berlin, he studied innate immune signal transduction using synthetic biology approaches. For his master thesis, Mauriz joined the lab of David Baker at the Institute for Protein Design at the University of Washington, designing allosterically regulated protein therapeutics. In his PhD, Mauriz will functionally characterize non-canonical human proteins combining genetic screens with proteomics and in silico modeling. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/114f5329-3b58-457f-b564-9775adc98afb/MichaelLim-018.jpg home - Michael Lim Michael earned his BSc (Honours) in Chemistry at the National University of Singapore where he gained an interest in chemical biology and interdisciplinary science. For his honours thesis, he worked in Ang Wee Han's lab on metal-ion enabled prodrug strategies for PROTACs. He joined the Winter lab in September 2024 to work on rewiring genome integrity. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/58c08beb-39f0-4d84-bc0a-7c1712e723f0/IakovosSaridakis-006.jpg home - Iakovos Saridakis Iakovos completed his PhD in organic chemistry at the University of Vienna under the supervision of Nuno Maulide, working on application-inspired targeted syntheses. These doctoral studies also included a research visit at the Daniele Leonori lab (RWTH Aachen), studying photoexcitation of nitroarenes. He joined the David MacMillan lab at Princeton University as a Max Kade (ÖAW) postdoctoral fellow working on photoredox catalysis and photo-proximity labelling. Iakovos joined the Winter lab in July 2025 as a PDRA to apply novel high-throughput chemical means and develop chemical inducers of proximity for rewiring regulated cell death. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/cfb4fc57-e532-4583-909d-be99c40bdfb2/CarolineSch%C3%A4tz-020.jpg home - Caroline Schätz Caroline studied Medical and Pharmaceutical Biotechnology at the IMC University of Applied Sciences in Krems. For her bachelor thesis she spent seven months at the Harvard Medical School in Boston working on tissue engineering using hypoimmunogenic stem cells. For her master thesis she was working on the development of advanced organoid systems in the group of Christoph Bock in Vienna. In October 2022 Caroline joined the Winter lab as a PhD student, where her research efforts focus on dissecting drug feedback mechanisms using genetic screens as well as chemical screens in organoids. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/f8a25f5f-6b68-4b2b-8c9c-7d7460135e5e/DmitriSegal-035.jpg home - Dmitri Segal Dmitri completed his PhD in molecular genetics at the University of Toronto under the supervision of Dr. Mikko Taipale. There, he utilized high-throughput interaction proteomics and high-content immunofluorescent imaging to decipher functional differences between 14-3-3 paralogs and uncover their chaperone-like functions. Dmitri joined the Winter lab in June 2023 as a postdoctoral fellow to identify and characterize novel proximity inducing compounds that rewire the function of specific transcriptional/epigenetic regulators in cancer. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/8c56c18f-4adf-4cd2-ae32-135269874ad3/MichelleShlei-016+Research+Technician+Winter+Lab.jpg home - Michelle Shlei Michelle earned her BSc in Microbiology and Genetics from the University of Vienna, which included a four-month research internship at the Medical University of Vienna specializing in bee venom allergy research. She subsequently completed an MSc in Immunology at the University of Vienna. For her Master’s thesis, she spent one year at the Institute for Laboratory Medicine, where she focused on optimizing lentiviral particle architecture to enhance targeted gene delivery to primary T cells for applications in functional genomics and cell therapy. She joined the Winter lab in 2026 as a research technician. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/39c216a7-dca1-4ac7-ad54-8b8d5c5676d0/DaniyaZakai-017.jpg home - Daniya Zakai Daniya acquired her Master's degree in Tissue Engineering and Regenerative Medicine at the FH Technikum Wien. She worked as a graduate student researcher at the School of Medicine UCLA and the Medical University of Vienna. For her Master thesis, she investigated cardiovascular abnormalities in Duchenne Muscular Dystrophy carrier rat models. In 2023, she joined Exscientia as a research associate, where she worked on developing a precision medicine platform for ovarian cancer using an ex vivo drug response assay. Recently, she joined the Winter lab as a research technician to support the development of degrader-antibody conjugates. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/2e369cd0-f4e0-4ed7-80fc-52c6b2f1be08/GeorgWinter-006.jpg home - Georg Winter Georg performed his graduate studies at CeMM in Vienna, working on elucidating the mechanism of action of cancer drugs with a specific emphasis on proteomics- as well as chemical genetics approaches. He continued his training in chemical biology, working as a postdoctoral fellow with Dr. James Bradner the Dana Farber Cancer Institute where he published the first paper reporting on in vivo target protein degradation and co-developed degron-tagging approaches that leverage the E3 ligase CRBN (dTAG approach) to understand the mechanistic involvement of gene control factors in oncogenic transcriptional circuits. He was recruited as a CeMM Principal Investigator in June 2016, continuing his work on targeted protein degradation with a particular emphasis on the phenotypic identification and mechanistic characterization of molecular glue degraders. In April 2025, Georg has been appointed as the Life Science Director at AITHYRA. Georg has authored more than 60 peer-reviewed papers and his contributions to the field of chemical biology in general, as well as targeted protein in particular, have been recognized via several international awards including the Eppendorf Award for Young European Investigators, the Wilson S. Stone Memorial Award from the MD Anderson, the Tetrahedron Young Investigator Award and the EFMC Price for Young Chemical Biologists. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/8cb34e89-34b1-4db4-ab97-c104b3a2a49d/Screenshot+2026-04-01+at+19.50.19.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/7e5415e2-2d2f-4cf6-b300-ea2f57d21879/Screenshot+2026-02-16+at+13.07.06.png home NEW MANUSCRIPT IN NATURE CHEMICAL BIOLOGY We are thrilled to announce the publication of our latest manuscript detailing a novel, scalable approach to identifying molecular glue degraders. By leveraging sulfur(VI) fluoride exchange-based high-throughput chemistry (HTC) to append structurally diverse building blocks to existing ligands, we identified novel degraders for ENL—a critical target in leukemia—and successfully unlocked the E3 ligase FBXO3 for degradation. This work was a fantastic collaboration with the Michael Erb lab, led on our end by PhD student Miquel Muñoz i Ordoño. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/42a78235-e8e9-455c-984c-34b2236da031/Screenshot+2026-01-14+at+10.22.43.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/92da55b6-eee1-48b4-afdb-de2a4d8ce98b/Screenshot+2026-01-16+at+10.35.34.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/efc9be04-eb77-4a77-a383-f8543e196a7b/Screenshot+2026-01-16+at+10.57.58.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/2ef95344-5e08-4fdc-8d5f-13a1941c1274/Screenshot+2026-01-16+at+11.28.40.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/1c21eda4-a099-4bc9-bbec-b9451a74d255/Screenshot+2026-01-20+at+11.04.59.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/77ec31d9-2b99-4c21-b8d5-812dc3aa0d53/Screenshot+2026-01-20+at+11.09.10.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/cae7747e-0235-4c5a-84f1-25b92ff582df/Picture1.png home - Mach es besonders Photo by Natascha Unkart. Credit to AITHYRA https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/2ad0470e-546e-460a-935a-6e46d709f794/Screenshot+2026-01-18+at+08.39.58.png home - Mach es besonders Photo by Natascha Unkart. Credit to AITHYRA https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/5df3ca77-a0cf-46fa-9651-db5a5b6bb52d/Screenshot+2026-01-16+at+11.05.48.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/00493aa9-9410-4d4a-82b9-f4fa7c6bec40/Screenshot+2026-01-16+at+11.07.00.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/5055a1dd-dad4-4465-8452-b40abc7ee407/CGC.jpg home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/3e048223-ae5f-4f22-ad6e-9187314fb610/LOGO-ERC.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/f891b732-fd9b-4510-a1aa-b918a9e1b63b/OEAW.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/0a4105c7-2c36-4c24-8bec-d187b83de9b9/EMBO.png home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/c2887bca-ea93-466e-9bfa-7619bc55a99f/csm_marie-curie_c29541d77f.jpg home https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/4b9ac0b4-5b29-4abd-88cd-2f8b556d9931/WWTF.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/4b3b8b0e-e8fe-41bc-8238-8d7b10e101a8/Screenshot+2026-01-21+at+07.53.50.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/e85268fd-b523-441a-a65f-b8b486be3d20/images.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/e8e5b366-93e4-4ac7-929c-2baf086e59ca/institutionlogo23106.jpeg home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/9cba87ed-5b36-4efb-a655-3df42dc0d0a0/FWF.png home - Mach es besonders Was auch immer es ist – die Art und Weise, wie du deine Geschichte online vermittelst, kann einen gewaltigen Unterschied ausmachen. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/3c23fb35-258d-4753-bd5b-9f39ac9a1ea3/fbc6a2a5-fea8-43ed-a4a8-74ce22f24350.JPG home Hiking with Alpacas at the Winter lab retreat. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/0d431b39-be10-49ce-8f7b-b9f9fbd0852b/DJMC0706.jpg home Chrysa and the Caro(s) at the fancy CeMM Christmas party. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/95a98954-fc51-46d9-9426-ab0f9779df2c/IMG-20250614-WA0003.jpg home - Mach es besonders Conquering our new lab space at AITHYRA. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/c59a6dc5-8b99-4370-8485-28f64e315ba3/IMG-20250925-WA0001.jpg home Iakovos’ transformation into a chemical biologist. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/ee2bfcae-4637-4d70-baef-75962bb40c43/IMG-20250925-WA0003.jpg home Caro and Marko demonstrating exemplary safety standards. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/37773b4d-63c0-4877-97d0-ba43aec8b646/IMG-20251028-WA0002.jpg home The Winter lab at the CeMM outing - Theater an der Wien. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/b5fc57a0-9c53-4cea-b849-b81f10e87ca3/IMG-20250813-WA0002.jpg home Summer time - ice cream time! https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/db854caf-31dc-4151-8615-c9064bf57761/IMG-20231025-WA0003.jpg home - Mach es besonders Meet the Flintstones at the Halloween party. https://images.squarespace-cdn.com/content/v1/5c7b791365a707d141caa67a/aea5f4ef-6388-4226-81bb-79336d4e5bd4/IMG-20220621-WA0022.jpg home A sporty adventure. https://www.winter-lab.com/neue-seite daily 0.75 2019-03-03 https://www.winter-lab.com/neue-seite-1 daily 0.75 2019-03-03